President of the Crosetto Foundation for the Reduction of Cancer Deaths
The 20 billion annually spent on cancer in Italy must not
create a competition between researchers but a union in publicly discussing
strategic plans that can defeat the common enemy that is cancer
by ALESSANDRO TERRADURA
We
continue in the deepening of this story, until now the claims have not been
contested because of maximum responsibility towards those who daily struggle
with this wild evil.
We
give space to a voice out of the chorus, because in this battle nothing must
remain untried, and we are open and we give space, verifying the authenticity of
the information, to every new voice that can contribute to the fight against
cancer.
We
resume asking questions to Mr. Crosetto referring to the articles published in
“Il Previdente” of November and December 2020, also available at (http://bit.ly/3okv90L) (http://bit.ly/3nQjpTS) and on the Facebook page United To
End Cancer (https://bit.ly/348Yrru) allowing to access numerous articles
in English and Italian, as well as the contacts of the Foundation which is one
of the non-profits in the United States that, by law, must publish the revenues
and tax returns available on the GuideStar website (https://www.guidestar.org/profile/03-0544575).
We met
several times and we wrote about you in regard to your creature, the 3D-CBS,
but who is Dario Crosetto, a scientist, a luminary, a dreamer who with his
invention fights against windmills, please explain it to us.
My
claims have proved and continue to prove correct year after year, as millions
of lives are lost unnecessarily as the transparency and scientific procedures
that address my inventions continue to be suppressed (over 20 million lives
have been lost unnecessarily around the world and over 1.2 million lives have
been unnecessarily lost in ITALY since my 3D-CBS invention in 2000) because
scientists, journalists and media do not want to express what they may not
agree on about my strategic plan (https://bit.ly/2THZmt9) and do
not want to test on a sample population how many lives the existing EXPLORER
device (less efficient, but basically copied from my invention) can save
each year and then use my 3D-CBS device (3-D Complete Body Screening) for
comparison.
I
have worked and designed the advanced instrumentation for the largest
experiments at the main research laboratories in the world: CERN,
Superconducting Super Collider -SSC-, FERMILab, Brookhaven National Laboratory,
etc. (2-page bio goo.gl/XQ3JyY and
testimonials goo.gl/VXBx33).
I
was hired first at CERN in Geneva and since 1991 at SSC in Texas. I have held
seminars in the most prestigious universities and research centers in the world
(Germany, France, Belgium, United States, Canada, Japan, Columbia, Mexico,
Argentina, Ghana, SriLanka and China) and at the best university hospitals and
research centers on cancer in Italy and Geneva, Switzerland, and written five
books and over 100 articles, reporting inventions supported by calculations and
proven feasible and working claims that create a paradigm shift in the field of
object recognition in very high-speed real-time applications, in particle
detection and medical imaging.
I
have demonstrated how the proof of concept of my invention works in hardware circuits,
confirming its advantages, but funding for a complete system has gone to less
efficient and more expensive approaches due to the lack of accountability to
taxpayers and donors who made donations.
I
received $1 million in research grants from the US government. I was entitled
to 20% of 1 million in total salary during the entire period of the research
grant, instead I used most of this money to buy electronic components in order
to advance the research.
With
the remaining 80%, I hired 4 young people and paid the best professional
consultants in the industry such as Synopsys and reported my findings in a 45
page article formally approved in peer review and published in one of the most
prestigious scientific journals (goo.gl/bqhD4R).
I
continued to work for free for 20 years placing others in the first place using
all the funds received as donations for others to advance in research.
Can you
summarize how the idea was born and what are the potential of 3D-CBS?
We
must go back to the 3D-Flow invention that overcomes the limits in recognizing
objects from the analysis of data arriving from thousands of electronic
channels at a very high-speed that I had invented to discover new subatomic
particles in the experiments of the most important research centers in the
world of CERN of Geneva and of the SSC in Texas.
The
scientific merit of the 3D-Flow invention was officially recognized in 1993 in
an international public scientific review (goo.gl/zP76Tc) of the utmost importance
held at the FERMILab in Chicago which was requested by the Director of the SSC,
also Director of Fermilab.
The
3D-Flow was adopted by thousands of scientists from the half-billion dollar GEM
experiment at SSC. However, the US Congress through the US Department of Energy
canceled the entire $11 billion SSC project which also included the GEM
detector.
In
1995 my 3D-Flow invention was adopted by hundreds of scientists from the LHCb
experiment at CERN in Geneva. However, in 1999 the US Department of Energy cut
all funding for the LHCb and ALICE experiments at CERN.
My
3D-Flow invention has been replaced by a more expensive, older design, less
efficient because research funds, as reported in the October 2018 article in
Scientific American (https://bit.ly/369yNDZ)
don’t go to the best projects, but to the researchers who have the best
connections.
Finding
myself for the second time with the realization path of my invention
interrupted for political reasons and/or unfortunate reasons and also because
the return in benefits to humanity from the discoveries in particle physics is
typically 35-40 years, I wondered if I could contribute to the solution of
the most serious problems for humanity with a return in benefits after 2-5
years instead of 35-40 years.
“I then
analyzed that the most deadly and costly problem in the world is cancer. I
realized from the study of experimental data that early detection can save the
lives of up to 98% of cancer patients and therefore wondered if it was possible
to design a cost-effective tool for the early detection of most cancers.
present throughout the body.”
Since
January 2000, I have therefore spent five months in the library of Dallas UT
Southwestern Medical Center major university hospital studying all major medical
imaging devices. I have found two types: those that measure and visualize the
density of tissues (X-rays, MRI, Mammography, Ultrasound, CT, etc. and those of
Nuclear Medicine that measure and visualize anomalous biological processes even
before a morphological change occurs (SPECT and PET) SPECT is very inefficient
and captures about one signal in 300,000 while PET build in 2000 captures about
one signal in 10,000.
In
PET (Positron Emission Tomography) I saw the possibility of an improvement in
efficiency of about 400 times. In June 2000 I wrote the book (goo.gl/ggGGwF) reporting in the first
half the state of the art of current PETs and in the other half I reported the
limits and technological innovations to overcome them.
I
have improved the efficiency of PET by 400 times by increasing the length of
the detector, improving the electronics, simplifying the detector assembly,
using thicker and economical crystal detectors, using a more precise pattern
recognition algorithm capable of capturing a greater number of signals from
tumor markers at the lowest cost per valid signal captured and by improving the
synergy between all components of PET (See the video at: https://bit.ly/31CLuG7).
Particle
physics and PET have in common the need to extract useful information from the
radiation with the big difference that if the system is inefficient, the
particle is discovered a few years later, without too much damage besides the
higher costs while instead there is a big difference in medical imaging applications:
an efficient PET saves lives, while an inefficient one mainly increases the
cancer business.
My 3D-CBS invention created a
revolutionary paradigm change in biomedical imaging in detecting the
abnormal functional activity of tumors the size of hundreds of cells in the
body instead of one billion cells (1 cm3) or one million cells (1 mm3),
even before any morphological changes that could be detected by a CT scan, MRI,
ultrasound, etc. have occurred.
Compared
to my previous work in physics experiments it was a matter of solving a problem
for a detector 25 times smaller identifying a single particle (a pair of
photons at 511 keV) while in the physics experiments I had to identify
electrons, hadrons, photons, muons, jets, etc.
Instead
of receiving the funds to make my inventions for the benefit of humanity,
influential colleagues in the scientific community who share the pie of
billions of dollars of taxpayers money for research, plagiarized and copied my
idea/invention, they boycotted my work, they have suppressed my publications
and presentations at scientific conferences. Some of them, belonging to three
US universities, appropriated several million dollars (the most significant in
a single research grant of $15.5 million), but not being able to build my idea/invention
they used American taxpayer money to commission the construction of a long PET
called EXPLORER to a Chinese company that confirmed my calculations in the
book (goo.gl/ggGGwF) that it could find tumors
with 100 cancer cells instead of a billion. However, an exam on the EXPLORER
costs over $10,000 (https://bit.ly/3554QnH)
instead of $200 on the 3D-CBS (https://bit.ly/2NvM57i,
50 times less).
This
confirmation that my 3D-CBS invention of the year 2000 could identify tumors
with 100 cells and could be built after the meeting I had on November 6, 2002,
with the executives of Siemens, the largest PET manufacturer in the world, when I had
solved the problem of inefficiency of their short PETs. They could have
verified my calculations on a longer PET by placing side-by-side 10 short PETs,
but they waited 18 years to do it with the Biograph Vision Quadra, only when
they feared losing a slice of the market threatened by the long PET EXPLORER.
The
market and technological advancement are not dictated by the benefits for
humanity of saving lives and saving money but by the profit of a few, in fact,
the other major PET manufacturer in the world has repeated to me for 20 years
that the market was not mature for long PETs… although I kept pointing out “…
the community is mature to receive the benefits of saving millions of lives and
saving billions of dollars”.
For 20 years I have been boycotted for proving that my invention can
identify tumors with 100 cancerous cells, now
that this has been confirmed I am boycotted in the strategy of carrying out
repetitive screening tests for $200 and with the help of CAD (Computer-Aided
Diagnosis) saving many lives and save a lot of money.
“I never thought there were so many
obstacles to do good to humanity”.
You
obviously take responsibility for what you claim and declare.
Of course, my statements
are based on analytical facts, I have nothing to hide, everything is published.
Your tireless
battle against an invisible enemy has finally seen the light. A parliamentary
question to the European Parliament, do you want to talk about it?
I
contacted parliamentarians and politicians from almost all political aisles
before I was able to find a person with the courage to present a question to
the European Parliament and I did not find any Representatives to present them
to the Italian Parliament.
On
this issue there are no political barriers that justify a party not to join due
to the presence of an opposing party. There are no political opponents in the
fight against cancer, but the one common enemy for all of us is cancer and we
must face this fight together.
I
contacted several Representatives of different colors and was baffled in the
way in which, except one, they disappeared for no reason, indeed just when they
realized that it was a serious matter, that I had been introduced to their
attention by a doctor, already member of the Italian National Superior Health
Council (Consiglio Superiore di Sanità) have vanished in the face of enormous
irrefutable inconsistencies to the detriment of citizens that need to be
addressed.
For
this fact, I underline the courage that the Representative who presented this
question had and I thanked him on behalf of cancer patients for being the
spokesperson for the interests of citizens on such an important issue that
overcomes every barrier and corporatism of a party against another, but which
reflects the sensitivity of His personality as an individual.
I
report the text of the Parliamentary Question and invite you to read it
officially translated into 24 languages on the European Union website. (https://www.europarl.europa.eu/doceo/document/E-9-2021-003244_EN.html).
“Subject: 3D-CBS
project [Full document at: https://bit.ly/3hCdGPw]
The death rate from
cancer is very high and the need to have effective early diagnosis tools
available for large scale use is more essential than ever.
The European Union
financed phase I of the WPET project, an overcoat for cancer screening weighing
over 350 kg and to be worn for 24 hours. This has now been modified for phase
II of the project with an application for over two million euro in funding for
a jacket that is not suitable for early diagnosis and weighs 10 kg.
Twenty years ago a
project for 3D-CBS (3D complete body screening) was devised. This has the
following advantages: 1. it can identify clusters of around a hundred cancer
cells before they grow to be a billion cells in 1 cm3 and would
therefore save the lives of over 50 % of the people who take the screening
test; 2. it only requires a very low level of radiation.
In light of
third-party measurements that confirm the efficacy of the 3D‑CBS2 invention,
does the Commission plan to share an approved scientific study with operators
and members of the public, in view of its potential?“
We
are now awaiting a written response from the Commission to the European
Parliament which, coincidentally, on 15 July 2021 (https://bit.ly/2TigQ2W)
the European Beating Cancer Committee (BECA) presented a draft of 24 pages
entitled “Strengthening Europe in the fight against cancer – Towards a global comprehensive
and coordinated strategy” (https://bit.ly/3i3ONOj).
This
is the right time to concretely discuss the effectiveness of the strategies and
to compare the strategies presented in the 24 pages on 15 July 2021 in terms of
costs and lives saved in 5, 10, 20 and 30 years (https://bit.ly/3i3ONOj)
with my strategy described in 4 pages (https://bit.ly/2V516AN)
to save in EUROPE by calculating the proportion between the two tables, over 20
million lives from premature death from cancer and save over € 2.6 trillion
over the next 30 years, building 3,700 3D-CBS equipment over 18 years.
Do
you think that if you ask a Representative if he prefers to have a cancer
screening test for himself, his loved ones and the citizens he represents on an
equipment capable of identifying tumors of 100 cancerous cells that requires a
dose of radiation equivalent to that received during 3-5 intercontinental flights
versus a device that only finds tumors with a billion or several million cancer
cells and requires a dangerous dose of radiation he replies “I don’t
know“?
Do
you think that if you ask the same Representative if
now that my calculations published in my 2000 book (goo.gl/ggGGwF) which
have been experimentally confirmed on three types of equipment (EXPLORER, Biograph Vision Quadra from Siemens and PennPET-EXLPORER)
built by third parties that it is possible to
identify tumors with 100 cancerous cells even in the face of experimental
scientific evidence he/she will answer “I don’t think it is useful for
me, for my loved ones and for the citizens I represent and therefore I am not
interested“?
Do
you think that if you ask the same Representative if he/she admits that the Scientific
Review Panel appointed by the Italian National Superior Health Council CSS in
2004 to examine the 3D-CBS project/invention was wrong in the calculations and
evaluations (found in the documents in the archive http://bit.ly/3t0uiWj)
by rejecting the advantages of the 3D-CBS with long detector (stating that it
would not have provided advantages), which are now proven wrong by experimental
results, this Representative deems it necessary to examine the errors, the
damage done to citizens and urgently review the
strategy submitted in 4 pages (https://bit.ly/2V516AN)
to save over 2.6 million lives from premature cancer
death in ITALY and save over €355 billion over the next 30 years by building
500 3D-CBS devices over 18 years?
At this point, not only one Representative but
all Representatives should agree in presenting a Question to the Italian
Parliament that asks the persons responsible for the various Committees that
manage and/or define the strategies that cost Italians €20 billion annually for
the cancer and the Ministers of Scientific Research and Health to analyze my
strategy at (https://bit.ly/2V516AN)
and correct the errors of the CSS regarding the scientific review of the 3D-CBS
project of 2004.
The
Minister of University and Scientific Research, Dr. Gaetano Manfredi and the
Deputy Minister of Health, Dr. Pier Paolo Sileri were present and participated
on 12 December 2020 at the Conference of Italian Researchers in the World held in video
conference from Houston, Texas, together the RAI who took care of the
presentation of the Conference. They witnessed the outrageous and uncivil
behavior documented on Facebook (http://bit.ly/2LbRorX)
in which the organizers suppressed transparency in science, even making it
appear the opposite of their censorship actions and exclusion without taking
responsibility for providing a reason.
In
the event that a Representative or decision maker with responsibilities in the
sector believes that it is not useful and beneficial to have a device capable
of identifying 100 cancer cells rather than a billion or several million, I
invite you to tell this person to contact me because I would have useful
information to share.
I apologize
if I am repetitive but your statements are quite strong, I must point out that
you obviously take responsibility for what you claim and say and that I am
collecting in this interview.
Of
course, it’s all documented and documentable. A person very dear to me on
January 28, 2021 felt a mass touching her abdomen. The CT scan detected three
masses, the largest 7.4cm x 6.4cm x 9.0cm at the ovaries that turned out to be
tumors.
What
happened to her can happen to any of us. She has never smoked, does not drink,
is thin, goes to the gym, follows a healthy diet, walks every day, has
regularly done all possible screening tests available (mammography,
colonoscopy, etc.) and the most important screening tests every year among the
27 offered by www.lifelinescreening.com.
All
of these screening tests reassured her that she had no cancer, however, no
screening test was able to detect a primary tumor of more than two billion
cancer cells over the span of four to ten years before it broke its structure
and metastasized affecting other organs.
When
the surgeon, who specializes in ovarian tumors, opened her abdomen on March 8,
2021, he realized that those were secondary tumors and the primary one, 2.5 cm
with more than two billion cancer cells at the appendix, had been there for more than four
years (estimated 4 to 10 years) and was not detected by CT, ultrasound and any
existing medical imaging devices or procedures she has undergone in recent
years, including last on February 8, 2021.
My
3D-CBS device could have detected it years ago when it had fewer than 100
cancer cells. Had my 3D-CBS invention been funded 21 years ago, her tumor could
have been removed with a simple surgical procedure, before its structure broke
and metastasized into the peritoneum, affecting many other organs.
Instead
on March 8, 2021, the surgeon faced a disastrous situation when he opened her
abdomen because none of the medical imaging devices were able to detect it
before and had to remove, along with the tumors, the ovaries, the uterus, the
fallopian tubes and the appendix. The second surgeon on May 25, 2021, removed
the spleen, which was totally compromised, two small liver tumors, adipose
tissue tumors in the peritoneum, scraped the colon and pancreas attacked by the
cancer cells and started the HIPEC procedure that does circulate 14 liters of
chemotherapy fluid at 41 ° C in the abdomen for 90 minutes to kill cancer cells
at 40 ° C that metastasize in the peritoneum.
From
May 25, 2021 to July 28, I went to the hospital every day and can testify the
pain, suffering, vomiting, nausea, etc. who suffered this loved one and the
difficulties of doctors, surgeons, oncologists, nurses due to failure to
diagnose it early. She was in a coma, and induced coma for 6 days, with a
nasogastric tube and other catheters that are still present after more than two
months. She spent 13 days in intensive care, she suffered from pneumonia, half
a liter of fluid was taken from her right lung. She was intubated with the
ventilator for 5 days, which was removed for 3 days and put back on for another
3 days.
“What is needed in the future for my very dear person and millions
of people diagnosed with cancer is a safe screening test with my 3D-CBS invented
21 years ago, performing a screening test at $200/test every two months (three
to six months as recommended by the doctor), sensitive enough to detect activity
of clusters (tumors) with fewer than 100 cancer cells before a resumption of
cancer growth at one million (1 mm3) or one billion (1 cm3)
of cancer cells. Anyone who disagrees with this has a duty to express their
disagreement because it is a serious matter”.
We
understand from what you tell us that even in a battle for civilizations like yours
there is a world made of economic interests that are based on artfully imposed
machinations, solutions closed in the drawer or even muddy to keep the disease
business alive, but is it conceivable that nowadays the tools or the possible
solutions in the fight against cancer have to play with the game of big corporations,
while the people are dying?
Unfortunately,
what you say is the sad reality that “ the tools or the possible
solutions in the fight against cancer have to play with the game of big corporations,
while the people are dying“. You in Italy do not touch this reality
firsthand and you realize only if you read and inform yourself, while in the
small environment of everyday life we here in the United States, as in any
country with a private health care system in which the true interest of who
supplies it is not to render a service to the citizen, but to have a greater
profit, it is inevitable that we clash many times with this reality. How do you
make more profit? Unfortunately, the logical answer is: “denying a
service“.
So,
I am not surprised by your statement, but how can it be countered and ensure
that human dignity and the rights to healthcare are respected?
It
is necessary to expose the inconsistencies to the detriment of the weakest and
then in a civilized country, culturally advanced in respecting the laws of
nature (Science), the laws of the Country and the Constitution (“Rule of
Law”), the professional ethics or code of ethical conduct and the golden
rule, we must refer to these rules to invite to desist or punish those who
violate them.
It is not my intention
to insult, denigrate or defame anyone, but as a man of science I present
irrefutable data and propose experimental tests that allow me to verify with
measurements on a sample population the validity of my calculations and claims
to make emerge the truth and the inconsistencies in defense of Science and the
weakest deceived or damaged by those who violate those rules.
Then
it is needed the help of journalists and the media who inform citizens. By
creating awareness most of the time those who violate the rules listed above
correct themselves and/or take responsibility of their mistakes and if they do
not, one must resort to lawyers and the Courts.
A
great difficulty I have found is to make the citizen understand the
inconsistency and the logical step to solve it.
Galileo
had had a brilliant idea that had greatly disturbed the luminaries and the
Church. He had explained the arguments for and against the geocentric system
(earth at the center of the Universe) and heliocentric (The sun at the center
of the solar system) by setting up a dialogue between Salviati (heliocentric)
and Simplicio (geocentric) with the third interlocutor Sagredo who represents
the discreet reader who intervenes in discussions asking for explanations,
contributing with more colloquial arguments.
I
started a similar dialogue on Facebook (https://bit.ly/3kcugIQ)
by creating two characters: the CURIOUS and the REASONABLE and I intend to
continue this dialogue.
For
example, in this dialogue it emerges that ITALY spends €20 billion per year on
cancer (https://bit.ly/3qVv9pS),
while the only time that there has been a decrease in cancer deaths in Italy
has been treaty of 1,134 lives saved between 2012 and 2013 (https://bit.ly/3fUUDjW),
while in other years cancer deaths increased in the absence of a population
increase (https://bit.ly/3pv3qwe),
so the €20 billion/year mainly increased the cancer business.
In
the dialogue, REASONABLE explains that it is understandable even to a child
that those who manage our tax money are throwing billions of euros out of the
window (or nurturing the cancer business) without being able to reduce cancer
mortality, while there are people on the front line that give body and soul,
work for free, and some even give their lives (such as doctors, nurses, law
enforcement, and public service workers who died of COVID-19 to save others), even
without resources, to alleviate cancer suffering and mortality.
We
cannot change the history that suppressed my 3D-CBS invention causing the
unnecessary loss over the past 20 years of over 20 million lives and over $10
trillion that could have been saved, but we can change the future. If investigative
reporters create a DIALOGUE by interviewing myself and scientists who disagree
with my calculations and my claim that my 3D-CBS invention is capable of
saving 260 lives per machine per year, when paired with an existing successful
cancer treatment, and by implementing my four-page strategic plan (https://bit.ly/2NvM57i),
we could save over 100 million lives and save over $ 27 trillion in the next 30
years worldwide.
However,
there seems to be a sign of an openness to dialogue because on my birthday,
July 22nd, 2021, the 300-word abstract of the 3D-CBS (3-D Complete Body
Screening) project, presented at the international conference TBPET (Total Body
PET), was approved. This abstract in 5 days with the sponsorship of only $1/day
on Facebook reached over 100,000 people and received 2,400 “likes” (https://bit.ly/2Wchq3i)
Paper
submitted to the 2021 TBPET (Total Body PET) Conference (TBPET)
Title
Multi-3D-CBS
whole-body screening tests: a revolutionary invention making diagnosis based on
CAD trends calculated on anomalies in biological processes, rather than on a
single examination, for saving millions of lives and trillions of dollars
Dario B. Crosetto – Crosetto Foundation for the
Reduction of Cancer Deaths – DeSoto, TX – USA.
Abstract
Background: 3D-CBS (3-D Complete Body Screening) [1] first true paradigm change in
biomedical imaging invented 21 years ago, confirmed by third party measured results on a 3D-CBS copy as able to safely detect clusters (tumors)
of 100 cells instead of one-billion cells (1cm3).
Materials and methods: 157cm-FOV 3D-CBS capable
of detecting all possible 511keV-pairs of photons from the tumor markers at the
lowest cost/valid pair captured, with components costing less than
$2,000,000/device, $200/2-minute screening test, and $1,200/15-minute clinical
exam, in two 8-hour shifts can safely perform 360×2-minute tests, 8×15-minute
exams [2]. It is estimated 48 professionals/day are needed: 8-administration,
4-logistic, 8-nurses, 8-technologists and 20-doctors (@$400,000/year salary),
each doctor reading 16-20 screening tests/day for 22 minutes each and
1-clinical exam for 68-minutes. People must perform several screening tests on
the same machine, using the same protocol and radiation dose. To avoid false
positives, the diagnosis will not be based on a single screening test but on
the Computer-Aided Diagnosis (CAD) tool calculating trend of anomalies in
several screening tests and radiologist’s experience. The first screening test
provides a baseline. Subsequent screenings reveal unique hot spots showing
increased activity/size of an anomalous biological process requiring deeper
investigation (15-minute clinical examination). Screening tests before/after
surgery detect if any cancer cells have been left over and monitor for
recurrences at an early curable stage.
Results: 90,000/test/year/device,
57billion tests/30-year on 57,000x3D-CBS/devices built gradually in 30-years
can save over 100,000,000 lives and over $27trillion [3] (Figure-1).
Conclusions: Because early cancer detection can save up
to 98% lives, an experimental test on a sample population of this approach
based on the CAD trend calculation over several 3D-CBS screening tests will
definitively prove that we can save millions of lives and trillions of dollars.
[1]-Crosetto, D. Book-2000-ISBN-0-9702897-0-7-
goo.gl/ggGGwF
[2]-Crosetto,
D. Article-2020-https://bit.ly/2NFkJbK
[3]-Crosetto, D. Calculations/Claims-2021- https://bit.ly/3gTXdHl
Parliamentary Question
published on the website of Honorable Panza:
(https://www.europarl.europa.eu/doceo/document/E-9-2021-003244_EN.html)
